p-gp(P-糖蛋白药物相互作用)

内容。2。3 不同药物通过p-gp对地高辛的影响。4。地高辛及胺碘酮DDI总结。P-糖蛋白的概念。Polymorphisms in Human MDR1 (P-glycoprotein): Recent Advances and Clinical Relevance Clinical Pharmacology & Therapeutics 75, 13-33 (January 2004)。P-糖蛋白的分布。P-gp tissue distribution. Efflux activity associated with P-gp would reduce intestinal drug absorption while enhancing drug..